Bone turnover helps accomplish long-term correction of the extracellular calcium (Ca^sup 2+^^sub o^) homeostasis by the actions of osteoblasts and osteoclasts. These processes are highly regulated by the actions of hormones, most prominently parathyroid hormone (PTH), the release of which is a function of the Ca^sup 2+^^sub o^, and is regulated by the action of the Ca^sup 2+^-sensing receptor (CaR) in the parathyroid gland. Various mutations of the CaR gene give rise to gain or loss of functions leading respectively to hypo- or hypercalcaemic conditions. CaR could conceivably be a target for local changes in the Ca^sup 2+^^sub o^ in the bone microenvironment thereby acting as a 'growth ...

Related newspaper, magazine, and journal articles:

;

See all results. Or, try our Advanced Search.

We're searching over:

• 60 million articles
• 3,500 publications