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Role of hyoscine N-butyl bromide (HBB, buscopan ®) as labor analgesic

Introduction

Hyoscine N-butyl bromide (HBB, Buscopan TM ) is a derivative of hyoscine, which is extracted from the leaves of the Dubosia tree found mainly in Australia. It is known for its antispasmodic action and has been around since 1951. [1] HBB acts by inhibiting cholinergic transmission in the abdominal and pelvic parasympathetic ganglia, thus relieving spasm in the smooth muscles of gastrointestinal, biliary, urinary tract and female genital organs, especially the cervico-uterine plexus and thus aiding cervical dilatation. [2],[3] Uterine contractions are not affected, [3] rather due to better co-ordination between uterine contractions and cervical dilatation, the latter is ...

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