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A prospective clinical review of "multi model" approach for treating ear keloids
- Article from:
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Indian Journal of Plastic Surgery
- Article date:
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January 1, 2008
- Author:
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;
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Copyright informationCopyright Medknow Publications Jan-Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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Introduction
It is well known that keloids are "Confused scars that do not know when to stop growing". The basic pathology is an imbalance between anabolic (proliferation) and catabolic (apoptotic) phases of the healing process. [1]
The various treatment modalities so far described in managing keloids are [2],[3] surgical excision, intralesional steroidal injections, compression therapy with silicon sheets, cryotherapy, laser, α-2b interferon and chemotherapeutic agents like 5-fluorouracil. Surgical excision totally eliminates the lesion but the main disadvantage is ≥50% recurrence [3] if used alone. The disadvantage with the other procedures is incomplete ablation of the lesion ...