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The Effect of the Number of Biopsy Cores on the Concordance Between Prostate Biopsy and Prostatectomy Gleason Score: A Prostate Volume-Controlled Study
- Article from:
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Archives of Pathology & Laboratory Medicine
- Article date:
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June 1, 2008
- Author:
- Antunes, Alberto A; Leite, Katia Ramos; Dall'Oglio, Marcos F; Cury, Jose; Srougi, Miguel
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Copyright informationCopyright College of American Pathologists Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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* Context.-Studies analyzing the concordance of biopsy and radical prostatectomy (RP) Gleason scores have limitations. Some included 2 or more centers, used historical controls from the early prostate specific antigen era or lacked a clear definition of the biopsy schemes. Furthermore, most did not control the results for prostate volume.
Objective.-To confirm whether prediction of RP Gleason score can be optimized by taking more biopsy cores in a contemporary series of patients, with pathologic samples analyzed by the same pathologist, and controlling these results for prostate volume.
Design.-The study comprised a retrospective case-control analysis of 393 patients with prostate cancer ...