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Dendritic cells based immunotherapy of patient with chondrosarcoma - case report
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Folia Histochemica et Cytobiologica
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April 1, 2008
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Copyright informationCopyright Folia Histochemica et Cytobiologica 2008. Provided by ProQuest LLC. (Hide copyright information)
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Abstract: We present a case report of patient with intracranial chondrosarcoma and attempt to use vaccination of dendritic cells as the salvage therapy. To our knowledge, this is the first case report of DCs vaccination in the head and neck chondrosarcoma. Immunotherapy with allogeneic DCs stimulated with tumor cell lysates in this case was demonstrated to be feasible, safe and well tolerated. Unfortunately we did not observe any clinical or immune response during vaccination. CD4+ and CD8+ regulatory cells could be responsible for ineffectiveness of immunotherapy.
Keywords: Chondrosarcoma of the head and neck - Dendritic cells - Immunotherapy
Introduction
Chondrosarcoma constitute nearly ...
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