TUMOR-ASSOCIATED PROTEOLYTIC FACTORS uPA AND PAI-1: Critical Appraisal of...

Critical Reviews in Clinical Laboratory Sciences;  March 1, 2007 ;     700+ words ......protease urokinase-type plasminogen activator (uPA), and its inhibitor...uPA, urokinase-type plasminogen activator; uPA-R, urokinase-type plasminogen...protease urokinase-type plasminogen activator (uPA), and its inhibitor...

Plasminogen activator inhibitor-1 levels and polymorphisms: Association...

Archives of Pathology & Laboratory Medicine;  November 1, 2002 ;     700+ words ......relationship between levels of plasminogen activator inhibitor1 (PAI-1) or the 4G/5G...bibliographies. Data Synthesis.-Plasminogen activator inhibitor-1 is an important inhibitor...Pathol Lab Med. 2002;126:1401-1404) Plasminogen activator inhibitor-1 (PAI-1) is the primary...

California Inventors Develop Urokinase Plasminogen Activator

US Fed News Service, Including US State News;  October 5, 2007 ;     382 words ......Jolla, Calif., have developed a urokinase plasminogen activator (uPA) active site-targeting peptide compound. According...residues 13-30 of the uPAR-binding site of uPA; competes with labeled DFP-uPA for binding to a cell or molecule that has...

IDENTIFICATION OF CELLS RESPONSIBLE FOR UROKINASE-TYPE PLASMINOGEN...

In Vitro Cellular & Developmental Biology;  March 1, 2004 ;     700+ words ......Human urokinase-type plasminogen activator (uPA) is a serine protease...kidney cell types with uPA synthesis. In addition, secretion of uPA activity into growth and uPA production media was...synthesize and secrete uPA into the culture medium. Key words: urokinase ...

t-plasminogen activator inhibitor-1 polymorphism in idiopathic pulmonary...

Indian Journal of Human Genetics;  May 1, 2008 ;     700+ words ......described for IPAH. Plasminogen activator inhibitor-1 (PAI-1...inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA). [3] The activators...degradation of the fibrin. Plasminogen activator inhibitor-1 is an...risk of thrombosis. Plasminogen activator ...

Breast cancer options made clearer.(research indicates concentrations of...

Science News;  April 22, 2000 ;     381 words ......researchers studied urokinase-type plasminogen activator (uPA) and its inhibitor, called PAI...Technical University of Munich measured uPA and PAI-1 concentrations in tumor...women with high concentrations of uPA and PAI-1 who got chemotherapy...

Restoration of hearing loss with tissue plasminogen activator: Case report

The Annals of Otology, Rhinology & Laryngology;  August 1, 2003 ;     700+ words ......left ear was treated with tissue plasminogen activator (tPA) for myocardial infarction...KEYWORDS - sudden hearing loss, tissue plasminogen activator. INTRODUCTION The factors responsible...particularly recombinant tissue plasminogen activator (rtPA) and single-chain urokinase...

The effects of urokinase-type Plasminogen Activator (uPA) inhibition on...

Bulletin (Southern California Academy of Sciences);  August 1, 2002 ;     205 words ......and muscle tissue. Urokinasetype Plasminogen Activator (uPA) has been speculated to convert...order to determine the direct role uPA plays in neural crest migration...diuretic drug known to inhibit uPA. By knocking out uPA, it is possible...

Cell-Free mRNA Concentrations of Plasminogen Activator Inhibitor-1 and...

Clinical Chemistry;  March 1, 2007 ;     700+ words ......concentrations of plasminogen activator inhibitor-1 (PAI-1) and tissue-type plasminogen activator (tPA) mRNA in maternal...plasmin are tissue-type plasminogen activator (tPA)4 and urokinase plasminogen activator (uPA). Inactivation of uPA by various ...

Absence of profound hyperinsulinism in polycystic ovary syndrome is...

Gynecological Endocrinology;  June 1, 2003 ;     700+ words ......words: POLYCYSTIC OVARY SYNDROME, PLASMINOGEN ACTIVATOR INHIBITOR, THROMBOPHILIA ABSTRACT...syndrome (PCOS) patients, we studied plasminogen activator inhibitor (PAI-1) system components...activity (r = 0.43), and tissue plasminogen activator (t-PA) (r = 0.5). Correlations...

Appropriate Indications for Administration of tPA.(tissue-type plasminogen...

American Family Physician;  August 1, 2005 ;     700+ words ......potential treatment with tissue-type plasminogen activator (tPA). they also place this recommendation...intravenous recombinant tissue plasminogen activator in experienced centres in highly...Physician 2004;69:1665-74. (2.) Tissue plasminogen activator for acute ischemic stroke. ...

Maryland Inventors Develop Mutant Plasminogen Activator

US Fed News Service, Including US State News;  June 28, 2008 ;     387 words ......Stefansson of Gaithersburg, Md., have developed a mutant plasminogen activator. According to the U.S. Patent & Trademark Office: "Mutants of the human plasminogen activator inhibitor type 1 (PAI-1) protein are described which are...

Purification of c-phycocyanin from Spirulina fusiformis and its effect on...

Phytomedicine: International Journal of Phytotherapy & Phytopharmacology;  September 1, 2006 ;     700+ words ......c-pc-induced urokinase-type plasminogen activator in the cells. These...and [beta] subunits; uPA; Fibrinolysis Introduction...2004). Urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) are serine proteases...

tissue plasminogen activator (TPA)

The Mosby Medical Encyclopedia;      94 words ...The Mosby Medical Encyclopedia 10-01-1996 tissue plasminogen activator (TPA), a clot-dissolving substance produced naturally by cells in the walls of blood vessels. It is also manufactured synthetically...

Prospective Evaluation of Recombinant Tissue Plasminogen Activator (rtPA)...

Nephrology Nursing Journal;  June 1, 2001 ;     42 words ...Prospective Evaluation of Recombinant Tissue Plasminogen Activator (rtPA) with a Retrospective Comparison for Urokinase in Re-Establishing Blood Flow through Occluded Hemodialysis Catheters. J.M. Zacharias, C. Weatherston, & L.M. Vercaigne, Manitoba, Canada (A1072).