Magazine article from our research archive:

TRIPLOIDY AND FETAL HOLOPROSENCEPHALY

Holoprosencephaly (HPE) is a developmental abnormality characterized by congenital malformations of the forebrain and mid-face. There are variable types of HPE, ranging from severe alobar HPE with cyclopia, ethmocephaly, cebocephaly, or HPE-PMA, to microforms with microcephaly, corpus callosum agenesis/dysgenesis, mental retardation, ocular hypotelorism, or a single maxillary central incisor. Chromosomal aberrations, Mendelian mutations, and teratogens are known causes of HPE. HPE is associated with chromosomal abnormalities such as trisomy 13, trisomy 18, triploidy, del(2p), dup(3p), del(7q), del(13q), del(18p), and del(21q). Prenatal diagnosis of HPE may be associated with triploidy. ...

Related newspaper, magazine, and journal articles:

See all results. Or, try our Advanced Search.

Newsweek Harper's Magazine The Washington Post Chicago Tribune Crain's Chicago Business PRNewswire Pediatric News The Nation Advertising Age The Economist (US) A FREE trial gives you access to over 60 million articles! Access over 3,500 publications with a FREE trial!