Article: ^sup 18^F-FLT PET in Glioma Proliferation

Article: ^sup 18^F-Fluoro-L-Thymidine and ^sup 11^C-Methylmethionine as Markers of Increased Transport and Proliferation in Brain Tumors
The Journal of Nuclear Medicine;  December 1, 2005 ;     700+ words ......01). Uptake ratios of ^sup 18^F-FLT were higher in...radiotracer uptake of ^sup 18^F-FLT was low and significantly lower than that of ^sup 11^C-MET (SUV, 1.3 0.7...detected only by either ^sup 18^F-FLT (7 patients) or ^sup 11^C-MET (13 patients...modeling revealed that ^sup 18^F-FLT ...

Article: Pharmacokinetics and Biodistribution of ^sup 111^In- and ^sup 177^Lu-Labeled J591 Antibody Specific for Prostate-Specific Membrane Antigen: Prediction of ^sup 90^Y-J591 Radiation Dosimetry Based on ^sup 111^In or ^sup 177^Lu?
The Journal of Nuclear Medicine;  April 1, 2005 ;     700+ words ...^sup 111^In-Labeled antibodies and peptides have...used as chemical and biologic surrogates for ^sup 90^Y-labeled therapeutic agents. However, recent...significant differences in biodistribution between ^sup 111^In- and ^sup 90^Y-labeled agents. Yttrium...

Article: ^sup 99m^Tc-MAEC Complexes: New Renal Radiopharmaceuticals Combining Characteristics of ^sup 99m^Tc-MAG3 and ^sup 99m^Tc-EC
The Journal of Nuclear Medicine;  May 1, 2004 ;     700+ words ...^sup 99m^Tc-Mercaptoacetyltriglycine (^sup 99m^Tc-MAG3) and ^sup 99m^Tc-L,L-ethylenedicysteine (^sup 99m^Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of ^sup 131^I-orthoiodohippurate...

Article: Effects of Intracellular and Extracellular Concentrations of Ca^sup 2+^, K+, and Cl- on the Na+-Dependent Mg^sup 2+^ Efflux in Rat Ventricular Myocytes
Biophysical Journal;  July 1, 2006 ;     700+ words ...ABSTRACT Intracellular Mg^sup 2+^ concentration ([Mg^sup 2+^]^sub i^) was measured in rat ventricular myocytes with...indicator furaptra (25C). After the myocytes were loaded with Mg^sup 2+^, the initial rate of decrease in [Mg^sup 2+^]^sub i^ (initial...

Article: Development of a Novel ^sup 99m^Tc-Chelate-Conjugated Bisphosphonate with High Affinity for Bone as a Bone Scintigraphic Agent
The Journal of Nuclear Medicine;  December 1, 2006 ;     700+ words ...In bone scintigraphy using ^sup 99m^Tc with methylenediphosphonate (^sup 99m^Tc-MDP) and hydroxymethylenediphosphonate (^sup 99m^Tc-HMDP), it takes 2-6 h after an injection before imaging can start. This interval could be shortened with a new radiopharmaceutical...

Article: Processing of Generator-Produced ^sup 68^Ga for Medical Application
The Journal of Nuclear Medicine;  October 1, 2007 ;     700+ words ...The ^sup 68^Ge/^sup 68^Ga generator provides an excellent source of positron-emitting ^sup 68^Ga. However, newly available "ionic" ^sup 68^Ge/^sup 68^Ga radionuclide generators are not necessarily optimized for the synthesis of ^sup 68^Ga-labeled...

Article: Low-Affinity Na^sup +^ Uptake in the Halophyte Suaeda maritima1[C][W][OA]
Plant Physiology;  October 1, 2007 ;     700+ words ...Na^sup +^ uptake by plant roots has largely been explored using species that accumulate little Na^sup +^ into their shoots. By way of contrast, Nathe...its leaves. Here we report that cAMP and Ca^sup 2+^ (blockers of nonselective cation channels...

Article: ^sup 203^Pb-Labeled [alpha]-Melanocyte-Stimulating Hormone Peptide as an Imaging Probe for Melanoma Detection
The Journal of Nuclear Medicine;  May 1, 2008 ;     700+ words ...Peptide-targeted α-therapy with 7.4 MBq of ^sup 212^Pb-[1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-ReO-[Cys^sup 3,4,10^, D-Phe^sup 7^,Arg^sup 11^]α-MSH^sub 3-13^ (^sup 212^Pb-DOTA-Re(Arg^sup 11^)CCMSH...

Article: ^sup 99m^Tc-N-DBODC5, a New Myocardial Perfusion Imaging Agent with Rapid Liver Clearance: Comparison with ^sup 99m^Tc-Sestamibi and ^sup 99m^Tc-Tetrofosmin in Rats
The Journal of Nuclear Medicine;  December 1, 2004 ;     700+ words ...^sup 99m^Tc-[bis (dimethoxypropylphosphinoethyl)-ethoxyethylamine (PNP5...myocardial uptake and clearance kinetics and organ biodistribution of ^sup 99m^Tc-N-DBODC5 with ^sup 99m^Tc-sestamibi and ^sup 99m^Tc-tetrofosmin. Methods: Seventy-five...

Article: Comparison of ^sup 123^I and ^sup 131^I for Whole-Body Imaging in Thyroid Cancer
The Journal of Nuclear Medicine;  May 1, 2002 ;     700+ words ...We compared the diagnostic sensitivities of ^sup 123^I and ^sup 131^I whole-body imaging in differentiated thyroid cancer...thyroidectomized patients (3 previously treated with ^sup 131^I) were studied. After a period of thyroid hormone...

Article: Arabidopsis HMA2, a Divalent Heavy Metal-Transporting P^sub IB^-Type ATPase, Is Involved in Cytoplasmic Zn^sup 2+^ Homeostasis1
Plant Physiology;  November 1, 2004 ;     700+ words ...P^sup IB^-type ATPases transport heavy metal ions (Cu^sup +^, Cu^sup 2+^, Zn^sup 2+^, Cd^sup 2+^, Co^sup 2+^, etc.) across biological membranes. Several members of this subfamily are present in plants. Higher plants are the only eukaryotes where putative...

Article: Skeletal PET with ^sup 18^F-Fluoride: Applying New Technology to an Old Tracer*
The Journal of Nuclear Medicine;  January 1, 2008 ;     700+ words ...Although ^sup 18^F-labeled NaF was the first widely used...fell into disuse after the introduction of ^sup 99m^Tc-labeled bone-imaging agents. Recent comparative studies have demonstrated that ^sup 18^F-fluoride PET is more accurate than ^sup...

Article: Treatment with ^sup 177^Lu-DOTATOC of Patients with Relapse of Neuroendocrine Tumors After Treatment with ^sup 90^Y-DOTATOC
The Journal of Nuclear Medicine;  August 1, 2005 ;     700+ words ...Therapy with [^sup 90^Y-DOTA^sup 0^, Tyr^sup 3^]-octreotide (DOTATOC, where DOTA = tetraazacyclododecane tetraacetic acid and TOC = D-Phe-c(Cys-Tyr-D-Trp-Lys-Thr-Cys)-Thr(ol)) is established for the treatment of metastatic neuroendocrine tumors. Nevertheless...

Article: Differential Uptake of O-(2-^sup 18^F-Fluoroethyl)-L-Tyrosine, L-^sup 3^H-Methionine, and ^sup 3^H-Deoxyglucose in Brain Abscesses
The Journal of Nuclear Medicine;  December 1, 2007 ;     700+ words ...The amino acid O-(2-^sup 18^F-fluoroethyl)-L-tyrosine (^sup 18^F-FET) has been shown to be a useful tracer for brain tumor imaging. Experimental studies demonstrated no uptake of ^sup 18^F-FET in inflammatory cells but increased uptake has been...