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Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium
- Article from:
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In Vitro Cellular & Developmental Biology
- Article date:
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May 1, 2008
- Author:
- Liu, Jie; Rumsey, John W; Das, Mainak; Molnar, Peter; Gregory, Cassie; Riedel, Lisa; Hickman, James J
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Copyright informationCopyright Society for In Vitro Biology May/Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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Abstract We are attempting to recreate a stretch reflex circuit on a patterned Rio-MEMS (bio-microelcctromeehanical systems) chip with deflecting micro-cantilevers. The first steps to recreate this system is to be able to grow individual components of the circuit (sensory neuron, motoneuron, skeletal muscle, and muscle spindle) on a patternable, synthetic substrate coating the MEMS device. Sensory neurons represent the afferent portion of the stretch reflex are and also play a significant role in transmitting the signal from the muscle spindle to the spinal cord motoneurons. We have utilized a synthetic silane substrate N-1[3-(trimethoxysilyl) propyl) diethylenetriamine (DETA) on which to ...
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Genes That Control Ray Sensory Neuron Axon Development in the...
Genetics;
July 1, 2006 ;
Jia, Lingyun; Emmons, Scott W;
787 words
......studied how a set of male-specific sensory neurons in Caenorhabditis elegans establish...adult male, 9 bilateral pairs of ray sensory neurons innervate an acellular fan that serves...underlying topographic mapping of sensory neurons into target circuitry where the next...
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Encoding Olfactory Signals via Multiple Chemosensory Systems
Critical Reviews in Biochemistry and Molecular Biology;
November 1, 2007 ;
Ma, Minghong;
787 words
......which comprises several subtypes of sensory neurons expressing distinct receptors and...mammalian nose (Breer et al., 2006). Most sensory neurons in the MOE are ciliated olfactory sensory neurons (OSNs), which express G-protein-coupled...
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Demonstrating the stretch reflex: A mechanical model
The American Biology Teacher;
September 1, 2000 ;
Batavia, Mitchell; McDonough, Andrew L;
787 words
......in parentheses). Introduction: The Stretch Reflex During a check-up at a physician's...usually tests a patient's reflexes. The stretch reflex (also called deep tendon reflexes...hence, the knee jerks). Why Is the Stretch Reflex Important? The stretch reflex provides...
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Neuromuscular characteristics of endurance- and power-trained...
Research Quarterly for Exercise and Sport;
March 1, 2004 ;
Koceja, David M. Davison, Edwin Robertson, Christopher T.;
787 words
......neuromuscular mechanisms is the spinal stretch reflex. The reflex system was previously...changes occurring in the spinal stretch reflex loop as a result of chronic...be examined. As the spinal stretch reflex represents one of the simplest...
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Segmental distribution and morphometric features of primary sensory...
Folia Histochemica et Cytobiologica;
April 1, 2004 ;
Gajda, Mariusz; Litwin, Jan A; Adriaensen, Dirk; Timmermans, Jean-Pierre; Cichocki, Tadeusz;
787 words
......study was to identify the primary sensory neurons that innervate the tibial periosteum...perikarya were analyzed. DiI-labeled sensory neurons innervating the periosteum of the...SP-containing cells, regarded as primary sensory neurons responsible for perception of pain...
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The Conserved Proteins CHE-12 and DYF-11 Are Required for Sensory Cilium...
Genetics;
February 1, 2008 ;
Bacaj, Taulant; Lu, Yun; Shaham, Shai;
787 words
......lipophilic dyes from their surroundings in sensory neurons and are chemotaxis defective. In che-...expression is restricted to some amphid sensory neurons, suggesting a specific role in these...nematode C. elegans contains 60 ciliated sensory neurons, 28 of which are assembled into ...
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A BOUQUET OF RESPONSES: OLFACTORY NERVE CELLS EXPRESSING SAME RECEPTOR...
US Fed News Service, Including US State News;
February 2, 2006 ;
661 words
......researchers discovered that olfactory sensory neurons expressing the same receptor responded...of Sciences. "We assumed that the sensory neurons that express the same receptor would...one out of 1000," she says. All the sensory neurons expressing the same receptor merge...
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A comparison between antisense P75(NTR) oligonucleotides and neurotrophic...
In Vitro Cellular & Developmental Biology;
September 1, 2000 ;
Lowry, K S; Cheema, S S;
787 words
......factor-deprived dorsal root ganglia sensory neurons in vitro (Barrett, G.; Bartlett, P...and axotomized dorsal root ganglia sensory neurons in vivo (Cheema, S. S.; Barrett, G...leukemia inhibitory factor, on cultured sensory neurons derived from postnatal day 7 and 14...
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Being Young Means Feeling Young
The Scientist;
February 16, 2004 ;
Bucci, Mirella;
233 words
......nematode Caenorhabditis degans, destruction of particular sensory neurons can extend, or reduce, lifespan by as much as 30%. Joy Alcedo...at play in higher organisms such as humans.1 The worm's sensory neurons seem to be acting through both an insulin-like signaling...
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Increasing Sensor Flexibility Through Neuromodulation.
The Biological Bulletin;
April 1, 2001 ;
BIRMINGHAM, J. T.;
787 words
......modification of the motor program. Real sensory neurons are more flexible than typical robotic...many robots differ from biological sensory neurons in a fundamental way. A typical man-ma...response to a particular stimulus. Real sensory neurons are dynamic. The spike trains they...
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A Bouquet of Responses: Olfactory Nerve Cells Expressing Same Receptor...
Ascribe Higher Education News Service;
February 2, 2006 ;
787 words
......researchers discovered that olfactory sensory neurons expressing the same receptor responded...Academy of Sciences. We assumed that the sensory neurons that express the same receptor would...one out of 1000, she says. All the sensory neurons expressing the same receptor merge...
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Scientists Uncover Complex Smell-Processing System in Humans.
Knight Ridder/Tribune Business News;
February 14, 2003 ;
787 words
......olfactory system, a large family of sensory neurons inside the nose. The sense of smell...despite the rapid turnover of the sensory neurons, or brain cells, that reside in the...researchers now are studying how the sensory neurons may provide insights into possible...
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A nose is a nose is a nose
The Milwaukee Journal Sentinel;
February 14, 2003 ;
JOHN FAUBER;
787 words
......olfactory system, a large family of sensory neurons inside the nose. The sense of smell...despite the rapid turnover of the sensory neurons, or brain cells, that reside in the...researchers now are studying how the sensory neurons may provide insights into possible...
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The spasticity evaluation test (SeT): A pilot study
Journal of Rehabilitation Research and Development;
January 1, 2001 ;
Marchese, Sandro S; Di Bella, Paolo; Sessa, Edoardo; Donato, Stefano; Bramanti, Placido;
787 words
......elbow, muscular force, spasticity, stretch reflex. INTRODUCTION Spasticity, properly...resulting from hyper excitability of the stretch reflex, as one component of the upper motor...the relationship between speed and stretch reflex has been given by Wartemberg in 1951...
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Yale School of Medicine scientist receives award for pain research.
M2 Presswire;
May 9, 2005 ;
364 words
......channel expression within higher-order sensory neurons of the pain pathway. These changes in sodium channel expression cause the sensory neurons to fire signals abnormally and manifest...sodium channels within higher-order sensory neurons of the pain-signaling pathway. Commenting...
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