Articles > Journals > Medical journals > The Israel Journal of Psychiatry and Related Sciences articles > January 2008

Article: Omega-3 Polyunsaturated Fatty Acids in the Treatment of Schizophrenia

Article from:
The Israel Journal of Psychiatry and Related Sciences
Article date:
January 1, 2008
Author:
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Abstract: Most studies have shown reduced levels of polyunsaturated fatty acids, particularly docosahexaenoic acid and arachidonic acid, in the cell membranes of red blood cells from schizophrenic patients. This has led to research interest in the possible therapeutic benefits of omega-3 fatty acids in schizophrenia. There is evidence from double-blind placebo-controlled trials that omega-3 fatty acids might prevent conversion from a prodromal state into first episode psychosis, and reduce the antipsychotic drug requirement in first episode patients. Results in chronic and acutely relapsing schizophrenia have been mixed. The problems associated with single nutrient studies are discussed. ...

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