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The Development of Biocomposite Nanofibers for Tissue Scaffolding Applications
- Article from:
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JOM
- Article date:
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June 1, 2008
- Author:
- Zhang, Y Z; Lim, C T
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Copyright informationCopyright Minerals, Metals & Materials Society Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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The last decade has seen significant progress in the production of nanoflbers by electrospinning. One of the major drivers to this progress is the potential use ofnanofibrous structures as scaffolds for engineering tissues in regenerative medicine. Electrospun fibers are capable of emulating the nanofibrous architecture of the native extracellular matrix. They can potentially provide in-vivo-like nanomechanical and physicochemical signaling cues to the cells to establish apposite cell-scaffold interactions and promote functional changes between and within cells toward synthesis of a genuine extracellular matrix over time. In this context, this paper presents a brief overview of a scaffold ...