Visionary Biomarkers

Applied Clinical Trials;  October 1, 2007 ;   Heverhagen, Johannes T; Knopp, Michael V;   787 words ......of one or two diameters of selected target lesions. Up to a maximum of five lesions per...involved organs, are identified as target lesions. The sum of the longest diameter for all target lesions is calculated. The response to treatment...

Pilot trial: NB-UVB not enhanced by tacrolimus

Dermatology Times;  May 1, 2005 ;   Guttman, Cheryl;   763 words ......therapy three times a week and had their target lesions randomized to twice daily treatment...completed the study, and responses of their target lesions were evaluated at four-week intervals...patients experienced improvement in all target lesions (mean improvement: tacrolimus ...

Rash in an adolescent.(Photo Quiz)

American Family Physician;  August 1, 2004 ;   Hackel, Joshua G. Nicholias, Vincent M. Morgan, J. Garris;   787 words ......pressure and later develop into classic target lesions that no longer blanch. Target lesions are diagnostic and have a central, dark-purp...does not always start with the typical target lesions but may begin with diffuse skin erythema...

NOVEL OCCLUSIVE patch IMPROVES RESPONSES TO TOPICAL PSORIASIS MEDICATIONS

Dermatology Times;  September 1, 2006 ;   Guttman, Cheryl;   787 words ......new hydrogel jwtch over one of the target lesions twice daily for eight weeks. Patients...study medications twice daily to both target lesions and a new hydrogel patch over one of the target lesions twice daily for eight weeks. Follow-...

Erythema multiforme.(Clinical Snapshot)(case report)(Clinical report)

Dermatology Nursing;  October 1, 2006 ;   Ruest, Amber Khachemoune, Amor;   787 words ......symmetrical fixed red papules, some of which evolve into target lesions (see Figure 1). A target lesion consists of concentric zones...precede/occur simultaneously or become evident after the target lesions of EM have appeared. Other infections that are clearly associated...

ADVENTRX Presents CoFactor Data at the 2008 Annual Meeting of the American...

PR Newswire;  June 3, 2008 ;     787 words ......rules for the measurement of tumor target lesions and involves techniques which measure...indicates the disappearance of all target lesions and a partial response (PR) indicates...the sum of the longest diameter of target lesions. A total of 32 patients were enrolled...

Use of computer-aided detection in thoracic CT

Applied Radiology;  December 1, 2007 ;   Roberts, Heidi C;   787 words ......algorithms are "trained" to select target lesions-those found and those missed by the...is not necessarily required that all target lesions are found; the overall sensitivity...defined as any CAD marks that are not target lesions. The rejection of false-positive marks...

36-Year-Old Man With Productive Cough and Diffuse Rash

Mayo Clinic Proceedings;  July 1, 2006 ;   Kumar, Gautam; Fadel, Hind J; Beckman, Thomas J;   787 words ......treatment. Examination of the patient's skin revealed atypical target lesions and areas of bulla formation affecting less than 5% of the...commonly during the warmer months; however, it does not produce target lesions. Rocky Mountain spotted fever is a tickborne illness caused...

Clobetasol foam, calcipotriene ointment a superb combination, study shows

Dermatology Times;  September 1, 2004 ;   Guttman, Cheryl;   787 words ......calcipotriene together or either agent alone, twice daily, to target lesions. Patients in the dual treatment group were instructed to...achieved a greater than 50 percent improvement of their target lesions continuing in a 24-week double-blind phase in which they...

Act fast with possible toxic epidermal necrolysis.(Dermatologic Therapy)

Skin & Allergy News;  October 1, 2007 ;   Walsh, Nancy;   687 words ......overlap syndrome. Erythema multiforme is characterized by target lesions that may blister, with little or no mucosal involvement...10% of body surface area plus mucosal involvement. The SJS-TEN overlap syndrome involves skin loss of 10%-30% of body surface...

Drug-induced skin conditions exhibit common characteristics

Dermatology Times;  September 1, 1998 ;   Blackmun, Susie;   787 words ......postinfectious and primarily herpes related. It presents as classic target lesions whose distribution is predominantly acral. The condition...greater than 30 percent. Patients are classified as having SJS/TEN overlap when they have widespread purpuric macules and the amount...

Erythema multiforme.(Disease/Disorder overview)

American Family Physician;  December 1, 2006 ;   Lamoreux, Michele R. Sternbach, Marna R. Hsu, W. Teresa;   787 words ......hypersensitivity reaction to infections or drugs. It consists of a polymorphous eruption of macules, papules, and characteristic target lesions that are symmetrically distributed with a propensity for the distal extremities. There is minimal mucosal involvement. Management...

Anaphylaxis and hypersensitivity syndrome reactions in increasing severity...

Journal of Postgraduate Medicine;  July 1, 2005 ;   Singbal, S; Rataboli, P;   787 words ......drugs. Erythema multiforme (EM) is an acute, usually self-limiting mucocutaneous disorder characterised by unique iritis or target lesions such as macules, papules, vesicles and bullae. Severe erythema multiforme with predominantly extensive bullous eruption...

Severe erythema multiforme.(Stevens-Johnson syndrome, Toxic epidermal...

Dermatology Nursing;  April 1, 2007 ;   Burfeind, Daniel B.;   787 words ......after the body reacts to a medication. SJS/TEN causes mucosal erosions with widespread erythematous, cutaneous macules, or target lesions that merge together with subsequent epidermal detachment. This can be an emotionally and socially devastating disease, especially...

Phase IIa psoriasis trial begins with topical ICAM-1 antisense inhibitor

Dermatology Times;  February 1, 2000 ;   Guttman, Cheryl;   571 words ......investigation, it will compare several different concentrations of the Isis 2302 preparation against placebo. Two individual target lesions will be identified in each patient and assigned to treatment with different study medications. Assessments will focus primarily...