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Co-infection with human immunodeficiency virus and tuberculosis

Introduction

The World Health Organisation (WHO) declared the global tuberculosis (TB) epidemic to be a public health emergency in 1993. Despite signs that the epidemic may be slowing down, the actual number of TB cases continues to rise. [1] HIV and TB are closely associated; HIV promotes the progression from latent TB infection to active disease and TB is the leading infectious killer of people living with HIV. The fight against HIV/AIDS and TB remains among the higher priorities for WHO.

Epidemiology

It is estimated that more than one third of the world's population is infected with Mycobacterium tuberculosis. In 2005, there were an estimated 8.8 million new active TB cases and 1.6 ...

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