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Early antiretroviral therapy: The pendulum shifts again
- Article from:
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Indian Journal of Dermatology, Venereology and Leprology
- Article date:
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May 1, 2008
- Author:
- Saple, D; Jindal, Saurabh; Vaidya, Satish
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Copyright informationCopyright Medknow Publications May/Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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Since the advent of highly active antiretroviral (HAART) in the mid-90s, the unequivocal benefit demonstrated by it in AIDS patients raised the question of the best time to initiate therapy. [1] Gradually, over the years, in response to increasing data, treatment schedules have changed from nucleoside reverse transcriptase inhibitors (NRTI) monotherapy to dual NRTI-based antiretroviral (ART) therapy and, most recently, to HAART. [2],[3] The euphoria over the efficacy of treatment initially led to a 'hit early-hit hard' [4] approach, which favored initiation of ART when the CD4 count decreased to less than 500 cells/cu mm or the plasma HIV RNA level rose to above 30,000 copies/ml. [5] This ...
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Winner of low milk cell count; DAIRY.(News)
Western Mail (Cardiff, Wales);
December 11, 2001 ;
195 words
......prize for having the lowest herd cell count in Wales. With a count of only 35...Carmarthenshire, with an average cell count of 44,000 cells/ml - still substantially below the current average cell count for Welsh herds of 183,000 cells...
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A money-saving move that backfired Peter Edmondson, from the Shepton...
Western Daily Press (Bristol UK);
September 25, 2007 ;
492 words
......came from a farmer whose payment average cell count had risen to more than 400 and he wanted...antibiotics to remove infection from the high cell- count cows, so that the problem would be resolved...However, life is never that simple. High cell-count cows are a symptom of an ...
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Peripheral blood CD34+ cell counts allow improved management of peripheral...
British Journal of Biomedical Science;
January 1, 2004 ;
Gibbs, G; Bolam, S;
787 words
......other indicators such as PB white blood cell count [WBC]) and the final CD34+ cell concentration...demonstrated a correlation between PB CD34+ cell count and harvest yield,1-9 while one has reported...correlation (r=0.94) between PB CD34+ cell count and the final concentration of ...
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Heart study underlines blood cell count.(NATION)
The Washington Times;
March 15, 2005 ;
457 words
......THE WASHINGTON TIMES A high white blood cell count may predict cardiovascular disease in...national research to assess white blood cell count as a gauge of cardiovascular events...recognized a connection between white blood cell count and cardiovascular disease risk in men...
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Cell count halved.(News)
The News Letter (Belfast, Northern Ireland);
November 25, 2000 ;
282 words
......particular, maintaining a low somatic cell count. His target this year was to reduce the cell count during the grazing season and he was advised...delighted to find a significant drop in the cell count. This continued as the grazing season...
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Differences important in assessing linear scores vs. somatic cell count
DVM;
March 1, 2000 ;
Gardner, Charles E;
787 words
......difference between linear scores and somatic cell count. The linear score is a logarithmic conversion of the somatic cell count, such that the linear score rises by one each time the somatic cell count doubles. Table 1 shows the relationship. If...
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WBC does not identify bacteremia in febrile infants.(Tips from Other...
American Family Physician;
February 15, 2004 ;
Sadovsky, Richard;
241 words
...Many physicians use a white blood cell count to screen for infection in infants with fever. Studies have found that white blood cell count analysis is not accurate in screening...The median total peripheral white blood cell count among infants with bacteremia was 13...
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Cell counts just keep on rising.(Farming Life)
The News Letter (Belfast, Northern Ireland);
July 21, 2001 ;
411 words
......to note that the trend towards rising cell count levels within British dairy herds mirrors...Foot-and-Mouth. There is a direct link between cell count levels and a disposition to clinical...impose stringent price penalties when cell count problems arise. Also, of great relevance...
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Donor endothelial cell counts do not determine dislocation rates in EK
Ophthalmology Times;
February 15, 2008 ;
Charters, Lynda;
787 words
......OR-A high preoperative donor endothelial cell count does not affect the rate of dislocation...aged 25 years or younger, an endothelial cell count of 4,000 cells/mm^sup 2^ or higher, and...will accept tissue with an endothelial cell count ≥2,000 cells/mm^sup 2^, a patient...
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Low blood cell count may be OK
Oakland Tribune;
July 7, 2008 ;
Dr Donohue;
386 words
......lab report shows that my white blood cell count is below normal. It has been 2,300, 2...appropriate A: You have had a low white blood cell count for 10 years. You haven't been sick in...Some medicines lower the white blood cell count. There's a list of other causes. You...
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Somatic cell count on the upward trend.(Features)
The News Letter (Belfast, Northern Ireland);
September 22, 2001 ;
675 words
......Development advisors are reporting that somatic cell count levels on some dairy farms are on an upward trend. The monthly average somatic cell count level for milk collected in NI for July...important role with regard to somatic cell count levels. But, of equal importance, it...
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Lupus Can Cause Antibodies, Low White Bloood Cell Count
Chicago Sun-Times;
August 21, 1992 ;
Dr. Paul Donohue; Paul G. Donohue (STANDARD);
223 words
...Q. I have seen lupus mentioned in regards to low white cell count. Now my daughter has been told she has lupus. Testing is not...in the general immunity disarray. In that regard, the white cell count is often depressed. That is a worst-case scenario. For most...
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Significance of white blood cell count during labor. (adapted from Family...
American Family Physician;
January 1, 1995 ;
307 words
......intensive care unit. The mean white blood cell count in the women before delivery was 12,450...classified as complicated. The white blood cell count in these complicated cases was slightly...significant. Women with a white blood cell count greater than 19,000 per L) had a 40 ...
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Graphite Nodule and Eutectic Cell Count in Cast Iron: Theoretical Model...
Metallurgical and Materials Transactions;
February 1, 2007 ;
Fras, E; Wiencek, K; Górny, M; López, H F;
787 words
......nodule count, N^sub A,n^, or eutectic cell count, N^sub A^, on polished cast iron surface...product of a graphite nucleation event, cell count measurements can be used to establish...In general, increasing the eutectic cell count in a given cast iron leads to the following...
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Changes in automated complete blood count and differential leukocyte count...
Archives of Pathology & Laboratory Medicine;
March 1, 2002 ;
Gulati, Gene L; Hyland, Lawrence J; Kocher, William; Schwarting, Rolland;
787 words
......parameters of automated complete blood cell count (CBC) and differential leukocyte count...CBC parameters, hemoglobin, red blood cell count, and mean corpuscular hemoglobin were...duration of the study (7 days), white blood cell count was stable for at least 3 days (up to...
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