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Article: Body weight set-points: Determination and adjustment
- Article from:
- The Journal of Nutrition
- Article date:
- September 1, 1997
- Author:
CopyrightCopyright American Institute of Nutrition Sep 1997. Provided by ProQuest LLC. (Hide copyright information)
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Body Weight Set-Points: Determination and Adjustment1
Richard E. Keesey2 and Matt D. Hirvonen
ABSTRACT It is proposed that body weight, like body water and body temperature, is physiologically regulated. In the case of body weight, coordinated adjustments in both the intake and expenditure of energy serve to stabilize the weights of individuals at a specified level and to resist their displacement from this level. Obese individuals also display these behavioral and metabolic adjustments to weight perturbations and thus appear to actively resist efforts to reduce their weight from the elevated levels they ordinarily display. Experimental studies of genetically transmitted and diet-induced ...