Magazine article from our research archive:
|
|
Need for the appraisal of uncommon side effects of a commonly prescribed drug- Imatinib
- Article from:
-
Indian Journal of Cancer
- Article date:
-
April 1, 2008
- Author:
-
;
;
|
Copyright informationCopyright Medknow Publications 2008. Provided by ProQuest LLC. (Hide copyright information)
|
Dear Sir,
The concept of targeted therapy is emerging as an innovative, high potential new trend in cancer therapy. These drugs are not supposed to affect the normal cells and act selectively on cancer cells there by minimizing the systemic side-effects. However the results are not as expected. One of such novel drugs (first of its kind to be approved by FDA) is Imatinib, a Bcr-Abl tyrosine kinase inhibitor. It has been used in patients of chronic myeloid leukemia and Gastro Intestinal Stromal Tumor (GIST) and has been under evaluation for many more indications. It is usually well tolerated, with relatively minor toxicities like fluid retention and skin changes. However, with the time, ...
Related newspaper, magazine, and journal articles:
|
Reporting of drug eruptions: The national pharmacovigilance program
Indian Journal of Dermatology, Venereology and Leprology;
January 1, 2005 ;
700+ words
......leukemoid reaction associated with carbamazepine hypersensitivity Indian J Dermatol Venereol Leprol 2005;71:35-7. 4. Prabhash K, Bapsy PP. Hydroxyurea induced non-healing leg ulcer. Indian J Dermatol Venereol Leprol 2005;71:50-2. 5. Sharma A, Vora A, Bhutani M...
|
 "The Daily Mail (London, England)")
|
Chemotherapy kills mother of three.
The Daily Mail (London, England);
September 17, 2008 ;
441 words
......that she died due to 5 Fluorouracil cardio-toxicity, a rare but documented side effect...were never informed of the risk of cardio-toxicity with 5 Fluorouracil. The coroner Dr...inquest, Mr Ryan said: The risk of cardio-toxicity was never pointed out to us. Even...
|
|
Brain uptake for anticancer drug
Pharmaceutical Technology Europe;
June 1, 2000 ;
142 words
......Further results, as yet unpublished, also demonstrated a significant decrease in doxorubicin concentration in the heart - cardio-toxicity being a major side effect of the drug. Tony Rees, Synt:em's director of sciences, hopes that the ability to effectively...
|
 "The Mirror (London, England)")
|
CHEMO RISKS NOT DISCUSSED.(News)
The Mirror (London, England);
September 17, 2008 ;
156 words
......her husband, Frank Ryan, that chemotherapy can have significant side-effects. But the couple were not told of the risk of cardio-toxicity with 5 - Fluorouracil. Mr Ryan said: If I felt if something lethal was possible I would have reacted differently, but I...
|
|
Pain Relief Network (PRN) Questions Anna Nicole's Autopsy Report: Drug...
PR Newswire;
March 26, 2007 ;
249 words
......as they should have been if drug overdose were the correct diagnosis? Or might Anna Nicole's death have resulted from the cardio-toxicity of methadone prescribed for her pain? ABOUT PRN Pain Relief Network is a network of pain patients, family members of people...
|
|
Monitoring of cardiotoxicity during immunotherapy with Herceptin using...
Clinical Medicine;
January 1, 2007 ;
700+ words
......ventricular ejection fraction (LVEF) as a method for detecting cardio-toxicity, whether by echocardiography, cardiovascular MR, or equilibrium-gat...testing is performed every three months and detection of cardio toxicity becomes to some extent 'retrospective'.1 Brain natriuretic...
|
|
Ropivacaine overdose and systemic toxicity
Anaesthesia and Intensive Care;
December 1, 2000 ;
700+ words
......again the high cardiovascular safety profile of ropivacaine. Experimental data have given evidence of a lesser neuro- and cardio-toxicity than racemic bupivacaine 12 and, in the recent literature, ropivacaine has shown less cardiovascular depressant effects...
|
 "Daily Herald (Arlington Heights, IL)")
|
Dangerous perceptions Highland Park organization spreads the word about...
Daily Herald (Arlington Heights, IL);
January 5, 2007 ;
700+ words
......of only two states that performed a test for ipecac when they did an autopsy. Carpenter's autopsy diagnosis was emetine cardio toxicity, emetine being the prime ingredient in ipecac. As part of their commitment to education and prevention, ANAD has initiated...
|
See all results.
Or, try our
Advanced Search.
|