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Gatifloxacin-induced rhabdomyolysis
- Article from:
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Journal of Postgraduate Medicine
- Article date:
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July 1, 2008
- Author:
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Copyright informationCopyright Medknow Publications Jul-Sep 2008. Provided by ProQuest LLC. (Hide copyright information)
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Flouroquinolone antibiotics cause musculoskeletal adverse effects like myalgia, arthralgia, tendon disorders and rhabdomyolysis. [1] Ofloxacin and levofloxacin rarely cause rhabdomyolysis, [2] but gatifloxacin has not yet been reported to cause rhabdomyolysis.
A 50-year-old male was admitted with intermittent fever and lower urinary tract symptoms for two days. No oliguria or dark urine was noticed. No alcohol abuse, illicit drugs, unprescribed medication use, unaccustomed exercise or trauma was present. A routine health evaluation two months prior was normal. Clinical examination at admission was unremarkable.
Renal failure (blood urea 52 mg/dl, serum creatinine 3.2 mg/dl, serum potassium ...