|
|
Parsing psoriasis
- Article from:
-
Dermatology Times
- Article date:
-
June 1, 2008
- Author:
-
|
Copyright informationCopyright Advanstar Communications, Inc. Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
|
Common DNA variations increase risk of developing skin condition
National report - Common DNA variations at seven newly identified sites increase the risk for psoriasis and psoriatic arthritis.
The whole genome association study of more than 300,000 single nucleotide polymorphisms (SNPs) was published in the March issue of PLoS Genetics. The goal was to identify new genes and new pathways for drug development.
The study first compared the genomes of 223 psoriasis patients, 91 of whom had psoriatic arthritis with a strong family history of psoriasis, with the SNPs of 519 health control subjects, looking for differences that could be linked to the diseases.
It then replicated the findings in ...