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Treating alopecia areata

Pilot study shows 'fascinating' potential synergism between bexarotene, oral corticosteroid treatment

Houston - Results of a pilot study suggest bexarotene deserves further exploration as a treatment for alopecia areata, according to investigators from the University of Texas M.D. Anderson Cancer Center.

Madeleine Duvic, M.D., discusses the outcomes from a phase 2, randomized, two-stage, bilateral comparison of bexarotene 1 percent gel (Targretin, Eisai/Ligand) in patients with alopecia areata (AA, 34 patients), alopecia totalis (AT, three patients), or alopecia universalis (AU, five patients).

After 24 weeks, 11 (26 percent) of the 42 enrolled patients achieved 50 percent or greater hair ...

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