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Endophthalmitis prophylaxis: limited evidence fuels controversy

Pros and cons

Baltimore-Protocols for prophylaxis of postoperative endophthalmitis remain controversial and vary widely among surgeons because of the paucity of Level I evidence to support specific interventions, said Oliver D. Schein, MD, MPII, at Current Concepts in Ophthalmology.

"While a large number of studies have been conducted to investigate endophthalmitis risk factors and prophylactic regimens, most are not rigorously designed, and the prophylaxis studies have been based primarily on surrogate outcomes," said Dr. Schein, the Burton E. Grossman Professor of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore. "Therefore, it is possible by ...

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