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Insulinoma: Reversal of brain magnetic resonance imaging changes following resection

Insulinoma can present with disorders of cognition, consciousness, epilepsy, psychosis, dementia and neuropathy. [1],[2],[3],[4],[5] Misdiagnosis and delay in treatment are common and may lead to prolonged hypoglycemia with permanent neurological deficit or fatal coma. [3]

Diagnosis depends on inappropriately high insulin levels in presence of hypoglycemia which could occur spontaneously or during prolonged fast. [5] Surgical removal of the tumor corrects the hyperinsulinemia and restores euglycemia.

But there is little literature on whether neurological deficit due to hypoglycemia-induced cerebral damage, which persists after correction of hypoglycemia, improves after surgical removal of ...

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