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The Influence of Maternal Early to Mid-Gestation Nutrient Restriction on Long Chain Polyunsaturated Fatty Acids in Fetal Sheep
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Lipids
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June 1, 2008
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Copyright informationCopyright AOCS Press Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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Abstract The early to mid-gestational period (days 28-78) in sheep is the period of most rapid placental development. Maternal nutrient restriction (MNR) in this phase has negative consequences on fetal growth and development, predisposing the fetus to disease in adult life. The influence of MNR on fetal tissue fatty acids has not been reported. Ewes were fed to 50% (MNR) or 100% (control fed) of total digestible nutrients from days 28 to 78 of gestation. At 78 days, fetuses were sacrificed and the fatty acids in fetal liver, lung and muscle as well as maternal and fetal plasma were analyzed. Most fatty acids were not influenced by MNR. The n-3 long chain PUFA eicosapentaenoic acid ...
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