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A Meal Enriched with Soy Isoflavones Increases Nitric Oxide-Mediated Vasodilation in Healthy Postmenopausal Women1,2
- Article from:
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The Journal of Nutrition
- Article date:
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July 1, 2008
- Author:
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Copyright informationCopyright American Institute of Nutrition Jul 2008. Provided by ProQuest LLC. (Hide copyright information)
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Abstract
Evidence from infusion studies suggests that soy isoflavones influence nitric oxide-dependent vasorelaxation. It is uncertain whether orally consumed isoflavones have similar effects. Healthy postmenopausal women (n = 22) consumed 2 low-fat test meals in random order 1 wk apart, with 80 mg isoflavones (ISO) or without isoflavones (CON). Endothelium-dependent vasodilation, assessed by brachial artery flow-mediated dilatation (FMD), was measured in fasting subjects, and 4 and 6 h following the test meal, in addition to blood pressure and pulse wave analysis to derive the peripheral augmentation index (pAlx). Blood samples were taken after fasting, and 5 and 7 h following the test ...
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