SCIENTISTS TO ASSESS EFFECTS OF MULTIPLE COPIES OF GENES ON DISEASE RISK

US Fed News Service, Including US State News;  January 29, 2007 ;     595 words ......technique to assess variations in gene copy number in 20 different mouse strains. According...about 10 percent of the genome features copy number variations," says Timothy Graubert...percentage of the genome, variations in gene copy number could explain more person-to-person...

Drive targets unsolved crimes

Yorkshire Post;  October 4, 2006 ;     446 words ......tandem with another big development - Low Copy Number DNA testing, which allows accurate matches...dormant in police files for decades. Low Copy Number, which was developed by a team of experts...role in securing the convictions. Low Copy Number showed that DNA found on the ...

Molecular typing of Mycobacterium tuberculosis isolates from different...

Indian Journal of Medical Research;  April 1, 2007 ;     700+ words ......245 bp IS6110 probe. Results: Based on the copy number, M. tuberculosis isolates were classified...groups, (i) lacking IS6110 element; (ii) low copy number (1-2); (iii) intermediate copy number (3-5); and (iv) high copy number (6-19...

Copy Number analysis software.(Bioinformatics Focus)

Bioscience Technology;  October 1, 2006 ;     191 words ...ArrayAssist Copy Number Software (Stratagene) is a guided workflow system that...analyze the massive data sets generated by chromosomal copy number microarrays. The Copy Number package is Stratagene's most recent application on the...

CHIMPANZEE STUDY REVEALS GENOME VARIATION 'HOT SPOTS'

US Fed News Service, Including US State News;  May 23, 2006 ;     644 words ......We found that chimpanzees have many copy number variants - duplications or deletions...udy's lead author, goes on to add: "These copy number variants may be very significant from...out that genetic differences such as copy number variants are there. And then you can...

DNA bomb charge teenager cleared

Belfast Telegraph;  February 2, 2008 ;     289 words ......because it relied on the Low Copy Number DNA, the forensic evidence that...questioned the reliability of Low Copy Number DNA, which relies on small samples...forensic matter. The UK allows Low Copy Number DNA to be used in court, but...

Terrorist charges dropped over DNA

Belfast Telegraph;  February 1, 2008 ;     283 words ......because it relied on the Low Copy Number DNA, the forensic evidence that...questioned the reliability of Low Copy Number DNA, which relies on small samples...forensic matter. The UK allows Low Copy Number DNA to be used in court, but...

DNA Analysis microarray.(Product News)

Bioscience Technology;  May 1, 2007 ;     112 words ......microarray targets regions of the genome that show copy number variation (CNV). Copy number variations can occur when a region within...chromosome is randomly amplified or deleted. DNA copy number of certain genomic regions can vary widely...

Copy Number Analysis of c-erb-B2 (HER-2/neu) and Topoisomerase II[alpha]...

Archives of Pathology & Laboratory Medicine;  January 1, 2005 ;     700+ words ......sensitive method for the measurement of gene copy number in clinical tumor samples. Objective...and highthroughput estimation of gene copy number in fresh, frozen, or paraffin-embedded...concordance between assessment of gene copy number of erb-B2 and TOP2A between quantitative...

Genome-Wide Comparison of Primate Genes Offers Insights Into Human, Great...

Ascribe Higher Education News Service;  July 15, 2004 ;     498 words ......which results in an increase in a gene's copy number. Gene duplications - as well as losses...significant majority of the major gene copy number changes that occurred over the past...genes with lineage-specific changes in copy number in specific primate lineages, 134 of...

Musician murder trial haltedin wake of Omagh judgment

Belfast Telegraph;  January 8, 2008 ;     523 words ......relation to the validity of the Low Copy Number DNA which formed part of the prosecution...in relation to the reliability of Low Copy Number DNA had impacted on the judicial system...the validity and reliability of Low Copy Number DNA. Mr Orr said his application followed...

Golden Helix CEO to Co-Chair MAQC Team

Wireless News;  May 2, 2008 ;     271 words ......Lambert, has been chosen to co-chair the Copy Number Variation Data Analysis Team within...Lambert presented promising genome-wide copy number association findings at the most recent...assay information. The inclusion of copy number variation is a logical progression to...

Murder case hit by DNA crisis.(News)

The Mirror (London, England);  January 8, 2008 ;     204 words ......finishes examining the validity of Low Copy Number DNA method. The issue was thrown into...Omagh bomb trial. He deemed that Low Copy Number DNA had not been validated by the international...Ireland which involve the system of Low Copy Number DNA. When asked about Mr Gilchrist's...

Magic numbers.

Australasian Business Intelligence;  April 18, 2006 ;     149 words ......techniques enabled scientists to conclude that copy number variations are equally important. Michael...evidence linking autism to variants in gene copy number. Some scientists believe that copy number variation may be more important than single...

GENETIC VARIATIONS BEHIND CHILDHOOD GLAUCOMA UNCOVERED

The Hindustan Times;  November 1, 2008 ;     257 words ......missing or extra bits of DNA called copy number variations are responsible for...closely and determined how these copy number variations occur. "Our findings...the mechanisms known to cause copy number variations, which improves our...