Gene discovery: key to colon cancer test. (gene that causes polyps that...

Science News;  August 10, 1991 ;     699 words ......researchers report the discovery of the APC gene in four papers: two in the Aug. 9 Science...people with FAP. One group pinned down the APC gene by finding many of the genes from band...Sciences Center in Salt Lake City, found the APC gene by searching for common mutations in the...

Gene Link Shared by Killer Cancers

Xinhua News Agency;  July 31, 2001 ;     272 words ......between bowel and breast cancer, because the APC gene is inactivated in different ways in the...bowel cancer, the DNA sequence of the APC gene is often mutated so that it reads incorrectly...Gen Tamura said, "We already knew the APC gene was important in bowel cancer, but to...

Copy Number analysis software.(Bioinformatics Focus)

Bioscience Technology;  October 1, 2006 ;     191 words ...ArrayAssist Copy Number Software (Stratagene) is a guided workflow system that...analyze the massive data sets generated by chromosomal copy number microarrays. The Copy Number package is Stratagene's most recent application on the...

Finding the Gene That Triggers Colon Cancer

The Washington Post;  August 13, 1991 ;     624 words ......magazine. If the same mutation in the APC gene occurs spontaneously after birth in a...than normal and form a polyp. "With the APC gene, we are looking at the earliest known...slow the rate of cell division. While the APC gene is now thought to trigger cancer, the...

New Test Reveals Breakthrough in Colorectal Cancer; Detection Study Shows...

Ascribe Higher Education News Service;  January 31, 2002 ;     679 words ......Medicine. The test reveals changes in the APC gene, a gene associated with colorectal cancer...protein markers derived from abnormal APC gene changes in stool samples, Dr. Levin says...earliest stages by identifying changes in the APC gene from a single stool sample, with no ...

DNA bomb charge teenager cleared

Belfast Telegraph;  February 2, 2008 ;     289 words ......because it relied on the Low Copy Number DNA, the forensic evidence that...questioned the reliability of Low Copy Number DNA, which relies on small samples...forensic matter. The UK allows Low Copy Number DNA to be used in court, but...

Research Money Well Spent

The Washington Post;  December 26, 1995 ;     230 words ......some people actually inherit a mutant APC gene from one of their parents. These unfortunate few, who have an APC gene mutation in every cell of their bodies...cancers not much later -- proof that APC gene mutations cause colon cancer. Public...

Terrorist charges dropped over DNA

Belfast Telegraph;  February 1, 2008 ;     283 words ......because it relied on the Low Copy Number DNA, the forensic evidence that...questioned the reliability of Low Copy Number DNA, which relies on small samples...forensic matter. The UK allows Low Copy Number DNA to be used in court, but...

Copy Number Analysis of c-erb-B2 (HER-2/neu) and Topoisomerase II[alpha]...

Archives of Pathology & Laboratory Medicine;  January 1, 2005 ;     700+ words ......sensitive method for the measurement of gene copy number in clinical tumor samples. Objective...and highthroughput estimation of gene copy number in fresh, frozen, or paraffin-embedded...concordance between assessment of gene copy number of erb-B2 and TOP2A between quantitative...

Musician murder trial haltedin wake of Omagh judgment

Belfast Telegraph;  January 8, 2008 ;     523 words ......relation to the validity of the Low Copy Number DNA which formed part of the prosecution...in relation to the reliability of Low Copy Number DNA had impacted on the judicial system...the validity and reliability of Low Copy Number DNA. Mr Orr said his application followed...

An Integrative Approach for Analyzing the Interplay of Genetic and...

Archives of Pathology & Laboratory Medicine;  October 1, 2008 ;     700+ words ......tumorigenesis that assumes that changes in DNA copy number always cause equivalent changes in the...Pathol Lab Med. 2008;132:1557-1561) DNA copy number changes have gained increasing attention...that were difficult to analyze for DNA copy number changes by conventional karyotyping...

Ty1 Copy Number Dynamics in Saccharomyces

Genetics;  March 1, 2005 ;     700+ words ......terminal repeat (LTR)-retrotransposon copy number dynamics, Ty1 elements were reintroduced...that Ty1 retrotransposition varies with copy number, temperature, and cell type. In contrast...constant and not markedly influenced by copy number. Endogenous Ty1 cDNA was poorly utilized...

Copy number a major source of variation

The Scientist;  May 1, 2006 ;     250 words ......controls for a cancer genome study, and "copy number differences jumped out at us," he says...arrays of 20 people, they found 76 unique copy-number polymorphisms (CNPs) of roughly 465...Reference] 1. J. Sebat et al., "Large-scale copy number polymorphism in the human genome," ...

Guided workflow for copy number software.(Instruments & Systems:...

Bioscience Technology;  February 1, 2007 ;     154 words ...ArrayAssist Copy Number Software (Stratagene Corp.) enables manipulation and analysis of the massive data sets generated by chromosomal copy number microarrays. All ArrayAssist applications offer GeneChip-compatible status with the Affymetrix platform...

Marker signals esophageal cancer.(Brief Article)

Science News;  December 9, 2000 ;     271 words ......application of the new findings may be a blood test for the active APC gene, Meltzer says. Further tests showed that three-fourths of patients...of such cancer. For example, a blood test showing that the APC gene is silenced might indicate the cancer is advanced and suggest...