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Article: The effects of estrogen therapy and estrogen combined with different androgenic progestins on carbohydrate and lipid metabolism in overweight-obese younger postmenopausal women
- Article from:
- Gynecological Endocrinology
- Article date:
- June 1, 2008
- Author:
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Copyright informationCopyright Taylor & Francis Ltd. Jun 2008. Provided by ProQuest LLC. (Hide copyright information)
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Abstract
Objective. The aim of the present study was to compare the effect of three different progestins with differing androgenicity on carbohydrate and lipid metabolism in overweight-obese younger postmenopausal women. Additionally, the relationship between testosterone and insulin resistance was assessed.
Methods. The study included 125 postmenopausal women. Estradiol (E^sub 2^) 2 mg/day was given to 20 hysterectomized women and the remaining 105 women were randomized into three treatment groups: E^sub 2^ 2 mg/day plus dienogest 2 mg/day (n = 35); E^sub 2^ 2 mg/day plus norethisterone acetate (NETA) 1 mg/day (n = 35); E^sub 2^ 2 mg/day plus medroxyprogesterone acetate (MPA) 2.5 mg/day (n ...
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