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Article: Perioperative catecholamine use and adverse cardiac outcomes
- Article from:
- Inpharma Weekly
- Article date:
- July 12, 2008
- Author:
CopyrightCopyright Wolters Kluwer Health Adis International Jul 12, 2008. Provided by ProQuest LLC. (Hide copyright information)
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Perioperative catecholamine use in heart surgery may be associated with an increased risk of postoperative adverse cardiac outcomes, according to results from a prospective nonrandomised cohort study.
Of the 657 patients who met the inclusion criteria, 84 patients received catecholamines intraoperatively and/or within 48 hours of cardiopulmonary bypass and were included in the 'catecholamine group'. The remaining 573 patients were included in the control group. In the catecholamine group, 89% of the patients received a low dobutamine dose for a short postoperative period. The study endpoints were major cardiac morbidity and overall mortality.
The researchers found that the incidence of ...