|
|
Article: Cellulose sulfate gel no role in HIV prevention
- Article from:
- Inpharma Weekly
- Article date:
- August 9, 2008
- Author:
CopyrightCopyright Wolters Kluwer Health Adis International Aug 9, 2008. Provided by ProQuest LLC. (Hide copyright information)
|
"Cellulose sulfate gel has no role as an HIV prevention method," conclude researchers in a study published in the NEJM.
In this study, designed to investigate the ability of cellulose sulfate gel to prevent HIV transmission, a total of 1398 HIV-negative women were enrolled and randomised to receive 6% cellulose sulfate gel or placebo gel, delivered in a 3.5-mL single-use opaque applicator. Women were asked to insert the gel into their vagina within 1 hour prior to vaginal intercourse over a period of 1 year. At the time of an interim data analysis, the study's independent data monitoring committee recommended that the study be halted due to a higher incidence of HIV infections in the active ...