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Treatment of Myeloma: Cure vs Control
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Mayo Clinic Proceedings
- Article date:
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October 1, 2008
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Copyright informationCopyright Mayo Foundation for Medical Education and Research Oct 2008. Provided by ProQuest LLC. (Hide copyright information)
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Although not often openly acknowledged, "cure vs control" is the dominant philosophical difference behind many of the strategies, trials, and debates related to the management of myeloma. Should we treat patients with myeloma with multidrug, multitransplant combinations with the goal of potentially curing a subset of patients, recognizing that the risk of adverse events and effect on quality of life will be substantial? Or should we address myeloma as a chronic incurable condition with the goal of disease control, using the least toxic regimens, emphasizing a balance between efficacy and quality of life, and reserving more aggressive therapy for later?
To be sure, if cure were known to be ...
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