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Effects of Diet and Age on Oxidative Damage Products in Healthy Subjects
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Physiological Research
- Article date:
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July 1, 2008
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Copyright informationCopyright Institute of Physiology 2008. Provided by ProQuest LLC. (Hide copyright information)
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Summary
Damage of molecules as a consequence of oxidative stress has been implicated in the pathogenesis of chronic diseases related to aging. Diet is a key environmental factor affecting the incidence of many chronic diseases. Antioxidant substances in diet enhance the DNA, lipid and protein protection by increasing the scavenging of free radicals. Products of oxidative damage of DNA (DNA strand breaks with oxidized purines or oxidized pyrimidines), lipids (conjugated dienes of fatty acids) and proteins (carbonyls) in relation to nutrition (vegetarian diet vs. non-vegetarian, traditional mixed diet) were measured in young women aged 20-30 years (46 vegetarians, 48 non-vegetarians) vs. ...
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