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Molecular Signatures of Lung and Pleural Tumors: Joint Symposium of the European Working Groups for Molecular Pathology and Pulmonary Pathology, 21st European Congress of Pathology

The intent of this special section on Molecular Signatures of Lung and Pleural Tumors is to describe new methodologic developments in molecular pathology to the general pathologist as well as to the specialist. Pathology in general and pulmonary pathology in particular have made dramatic steps forward in recent decades: In the mid 1980s, the advent of immunohistochemistry revolutionized our research and diagnostic work. Polymerase chain reaction and in situ hybridization for selected mRNAs followed in the early 1990s. Analysis of DNA by chromosomal hybridization and cDNA array were the next steps in this story of success, but these new techniques showed how contamination of tumor tissues ...

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