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Article: Acute allergic interstitial nephritis after use of pantoprazole
- Article from:
- Canadian Medical Association. Journal
- Article date:
- March 3, 2009
- Author:
CopyrightCopyright Canadian Medical Association Mar 3, 2009. Provided by ProQuest LLC. (Hide copyright information)
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CASES
The case: A 57-year-old man presented to hospital with a 2-week history of progressive malaise, myalgia, fever, nausea, vomiting, diarrhea, polyuria and polydipsia. He had a history of gastresophageal reflux that did not respond to ranitidine. He had started taking oral pantoprazole (40 mg daily) 6 weeks earlier. The patient had a history of coronary artery disease and was taking acetylsalicylic acid (81 mg daily) and atorvastatin (40 mg daily). He reported having taken ibuprofen (400 mg) for myalgia no more than 3 times over the 2-week period before presentation. He had no history of renal disease or drug allergies.
On presentation, the patient was afebrile (temperature 36.5°C), ...