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Direct current cardioversion of atrial fibrillation--the next 40 years
- Article from:
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Mayo Clinic Proceedings
- Article date:
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September 1, 2002
- Author:
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;
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Copyright informationCopyright Mayo Foundation for Medical Education and Research Sep 2002. Provided by ProQuest LLC. (Hide copyright information)
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Editorial
A trial fibrillation affects more than 2.5 million people in the United States. Almost 4 decades have passed since Lown et al1 first reported on successful direct current (DC) "cardioversion" of atrial fibrillation to sinus rhythm, thereby profoundly altering the treatment of the most common, sustained arrhythmia. Although restoration of sinus rhythm has been shown to provide symptomatic and physiologic benefits,2 it results in adverse events, including potentially catastrophic clinical thromboembolism in up to 6% of patients who are not receiving warfarin anticoagulation before cardioversion.3-5 Nonrandomized, relatively small series have suggested that 3 to 4 weeks of warfarin ...
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