Article: Acclimation during space flight: effects on human physiology

Patients on earth with illness can be described as people who live in a normal earth environment but who have abnormal physiology. In contrast, astronauts are people with normal physiology who live in an abnormal environment. It is this abnormal environment in space that, for the most part, causes unique alterations in astronauts' physiology that require the attention of clinicians and scientists. In this review, we build on the first article1 in this series and provide an overview of the many complex physiologic changes that take place in short- and long-duration space flight, most often in response to microgravity.

The goal of sending people farther into space and extending the duration ...

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