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Article: PET, CSF, and Preclinical Alzheimer's Disease
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- July 1, 2009
- Author:
CopyrightCopyright Society of Nuclear Medicine Jul 2009. Provided by ProQuest LLC. (Hide copyright information)
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DIAGNOSIS
Two articles published in May addressed the relationship between changes in cerebral glucose metabolism as assessed by PET and specific alterations in cerebrospinal fluid (CSF), both of which are associated with presymptomatic onset of Alzheimer's disease. Petrie et al. from the Veterans Affairs Puget Sound Health Care System (Seattle, WA) reported in the May issue of Archives of Neurology (2009;66:632-637) on a study designed to assess whether cerebral glucose metabolism and CSF levels of τ and Ã-amyloid peptide 42 in healthy individuals correlate in brain structures affected early in Alzheimer's. The study included 20 healthy individuals without dementia (age range, 46-83 ...