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Article: Bile Acids Conjugation in Human Bile Is Not Random: New Insights from ^sup 1^H-NMR Spectroscopy at 800 MHz
- Article from:
- Lipids
- Article date:
- June 1, 2009
- Author:
CopyrightCopyright AOCS Press Jun 2009. Provided by ProQuest LLC. (Hide copyright information)
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Abstract Bile acids constitute a group of structurally closely related molecules and represent the most abundant constituents of human bile. Investigations of bile acids have garnered increased interest owing to their recently discovered additional biological functions including their role as signaling molecules that govern glucose, fat and energy metabolism. Recent NMR methodological developments have enabled single-step analysis of several highly abundant and common glycine- and taurine- conjugated bile acids, such as glycocholic acid, glycodeoxycholic acid, glycochenodeoxycholic acid, taurocholic acid, taurodeoxycholic acid, and taurochenodeoxycholic acid. Investigation of these ...