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Article: Does Local Anesthetic Dilution Influence the Clinical Effectiveness of Multiple-Injection Axillary Brachial Plexus Block?

Article from:
Regional Anesthesia and Pain Medicine
Article date:
September 1, 2009
Author:
Copyright

A Prospective, Double-Blind, Randomized Clinical Trial in Patients Undergoing Upper Limb Surgery

Objectives: The relationship between the dose, volume, and concentration of local anesthetic and the quality and success of regional anesthesia remains unclear. Our aim was to test whether using 3 different volumes of the same local anesthetic dose influences the success rate of an axillary brachial plexus block with a multiple-injection technique in patients undergoing upper limb surgery.

Methods: One hundred sixty-five patients were prospectively randomized to 1 of 3 groups. Each group received an axillary block with mepivacaine 400 mg, diluted in 3 different volumes (20, 30, and 40 mL). ...

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