Article: Publication No. WO/2009/021121 Published on Oct. 29, Assigned to WYETH, Viropharma for Hcv Replicon Variant Characterization, Identification (American Inventors)

GENEVA, Oct. 31 -- Michael James Flint, Anita Y.M. Howe and Anne McClure Deatly, all from the U.S., have developed an identification and characterization of hcv replicon variants with reduced susceptibility to a combination of polymerase.

The patent has been assigned to WYETH, Madison, N.J. and Viropharma Inc., Exton, Pa.

According to an abstract posted by the World Intellectual Property Organization: "The present invention provides methods of decreasing the frequency of emergence, decreasing the level of resistance, and delaying the emergence of a treatment-resistant hepatitis C viral infection, by administering to a subject, either in combination or in series, an inhibitor of the ...

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