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Article: Quantification of area at risk in acute myocardial infarction by tomographic imaging
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- December 1, 1997
- Author:
CopyrightCopyright Society of Nuclear Medicine Dec 1997. Provided by ProQuest LLC. (Hide copyright information)
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The purpose of this study was twofold: to validate, in a phantom heart model, a simple threshold technique for the quantification of defect size using ^sup 123^|-15-(p-iodophenyl)-3-(R,S)-methyl pentadecanoic acid (BMIPP) imaging and to compare, in patients with acute myocardial infarction, defect size as shown by BMIPP imaging, with the extent of severe hypokinesis shown by left ventriculography. Methods: In a phantom study, defect size was calculated using a standard geometric formula. In a clinical study, BMIPP imaging was performed in 20 patients 10 +/- 5 days after the onset of their infarction. Using the centerline method, the area at risk was defined by contrast ventriculography as ...