|
|
Article: Algorithm analysis of lectin glycohistochemistry and feulgen cytometry for a new classification of nasa polyposis
- Article from:
- The Annals of Otology, Rhinology & Laryngology
- Article date:
- December 1, 1997
- Author:
CopyrightCopyright Annals Publishing Company Dec 1997. Provided by ProQuest LLC. (Hide copyright information)
|
The aim of this study is to present a new classification of nasal polyps. This classification is based both on morphologic criteria relating to morphonuclear features from isolated Feulgen-stained nuclei and on glycohistochemical characteristics from histologic slides submitted to three lectins (peanut, wheat germ, and gorse seed agglutinins) and one neoglycoconjugate glycohistochemical stain. While the morphonuclear features (including 30 variables) relate essentially to chromatin pattern, the glycohistochemical stains (including 16 variables) are linked to the presence of specific carbohydrate moieties in cell membranes and cytoplasm. Forty-nine nasal polyps, including single polyps, ...