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Article: Zinc transporters 1, 2 and 4 are differentially expressed and localized in rats during pregnancy and lactation
- Article from:
- The Journal of Nutrition
- Article date:
- February 1, 2003
- Author:
CopyrightCopyright American Institute of Nutrition Feb 2003. Provided by ProQuest LLC. (Hide copyright information)
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Zinc Transporters 1, 2 and 4 Are Differentially Expressed and Localized in Rats during Pregnancy and Lactation1
ABSTRACT Zinc metabolism is controlled within relatively restricted limits throughout the life cycle. Expression and localization of zinc transporters 1, 2 and 4 during pregnancy and lactation in small intestine, mammary gland and liver of the rat were investigated using Northern analysis, Western blotting and immunohistochemistry. In maternal tissues, zinc transporter 4 was the most widely expressed among these zinc transporters in the tissues examined. In small intestine and liver, zinc transporter 4 increased from levels found during late gestation, but zinc transporter 1 did ...