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Article: Red wine polyphenolics increase LDL receptor expression and activity and supress the secretion of ApoB100 from human HepG2 cells
- Article from:
- The Journal of Nutrition
- Article date:
- March 1, 2003
- Author:
CopyrightCopyright American Institute of Nutrition Mar 2003. Provided by ProQuest LLC. (Hide copyright information)
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Nutrient-Gene Interactions
Red Wine Polyphenolics Increase LDL Receptor Expression and Activity and Suppress the Secretion of ApoB100 from Human HepG2 Cells1
ABSTRACT Epidemiologic studies suggest that the consumption of red wine may lower the risk of cardiovascular disease. The cardioprotective effect of red wine has been attributed to the polyphenols present in red wine, particularly resveratrol (a stilbene, with estrogen-like activity), and the flavonoids, catechin, epicatechin, quercetin and phenolic acids such as gallic acid. At present, very little is known about the mechanisms by which red wine phenolic compounds benefit the cardiovascular system. Therefore, the aim of this study ...