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Article: Inflammatory demyelinating disease mimicking malignant glioma
- Article from:
- The Journal of Nuclear Medicine
- Article date:
- April 1, 2003
- Author:
CopyrightCopyright Society of Nuclear Medicine Apr 2003. Provided by ProQuest LLC. (Hide copyright information)
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The differential diagnosis between inflammatory demyelinating disease and malignant glioma is difficult based only on neuroimaging methods. Methods: Four patients with inflammatory demyelinating disease who presented with clinical and neuroimaging findings strongly suggestive of malignant glioma were examined. Results: MRI showed a mass lesion with prolonged T1 and T2 values and gadolinium enhancement in all cases. Proton MR spectroscopy and ^sup 201^T1 SPECT showed findings supportive of the diagnosis of malignant glioma in all cases. However, surgical biopsy revealed inflammatory demyelinating disease. After the diagnosis, 2 patients were treated by steroid administration and 2 were just ...