Article: Omalizumab appears effective in patients with poorly controlled allergic asthma

DENVER, COLO-Patients whose asthma was poorly controlled with conventional treatments and who received the investigational anti-immunoglobulin-E drug omalizumab experienced about half the number of asthma deterioration-related incidents as patients who did not receive the add-on medication.

Rob Niven, MD, a respiratory consultant at the North West Lung Research Centre, Manchester, United Kingdom, said that in the yearlong open-label study, patients receiving add-on omalizumab had an annualized rate of 4.92 events per patient year, compared with 9.76 per patient year for patients who continued to receive baseline treatment for their asthma (P<.001).

In his presentation at the 60th ...

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