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Article: Evidence for a circadian rhythm of susceptibility to retinal light damage
- Article from:
- Photochemistry and Photobiology
- Article date:
- May 1, 2002
- Author:
CopyrightCopyright American Society of Photobiology May 2002. Provided by ProQuest LLC. (Hide copyright information)
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Evidence for a Circadian Rhythm of Susceptibility to Retinal Light Damage^(para)
ABSTRACT
This study investigated a possible circadian rhythm of light damage susceptibility in photoreceptors of both cyclic light-reared and dark-reared rats. A single exposure to intense green light was administered, beginning either in the early light period, the late light period or the dark period. In some animals exposed in the dark period, the synthetic antioxidant dimethylthiourea was administered before or after the onset of intense light exposure. Retinas were examined either immediately after exposure or after 2 weeks of recovery in darkness. Rod outer segment length and outer nuclear layer ...