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Article: The effect of epidermal growth factor & platelet-derived growth factors on wound healing process
- Article from:
- Indian Journal of Medical Research
- Article date:
- November 1, 2002
- Author:
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Copyright informationCopyright Indian Council of Medical Research Nov 2002. Provided by ProQuest LLC. (Hide copyright information)
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Received April 12, 2002
Background & objectives: Various growth factors play significant roles during the process of wound healing. A systematic study was carried out to evaluate the effects of topically applied epidermal growth factor (EGF) and platelet-derived growth factors (PDGF-BB, PDGF-AB, PDGF-AA) in various concentrations on wound healing. Various combinations of these growth factors were also studied to find the best combination for wound healing.
Methods: Wounds were created on a mouse model. Various concentrations and combinations of EGF and PDGFs were applied topically and the effects on wound healing were monitored visually.
Results: EGF, PDGF-AB and PDGF-BB when applied ...