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Article: The effect of epidermal growth factor & platelet-derived growth factors on wound healing process

Article from:
Indian Journal of Medical Research
Article date:
November 1, 2002
Author:
Copyright

Received April 12, 2002

Background & objectives: Various growth factors play significant roles during the process of wound healing. A systematic study was carried out to evaluate the effects of topically applied epidermal growth factor (EGF) and platelet-derived growth factors (PDGF-BB, PDGF-AB, PDGF-AA) in various concentrations on wound healing. Various combinations of these growth factors were also studied to find the best combination for wound healing.

Methods: Wounds were created on a mouse model. Various concentrations and combinations of EGF and PDGFs were applied topically and the effects on wound healing were monitored visually.

Results: EGF, PDGF-AB and PDGF-BB when applied ...

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