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Iron and oxidative stress in pregnancy1'2
- Article from:
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The Journal of Nutrition
- Article date:
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May 1, 2003
- Author:
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;
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Copyright informationCopyright American Institute of Nutrition May 2003. Provided by ProQuest LLC. (Hide copyright information)
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ABSTRACT Pregnancy, mostly because of the mitochondria-rich placenta, is a condition that favors oxidative stress. Transitional metals, especially iron, which is particularly abundant in the placenta, are important in the production of free radicals. Protective mechanisms against free radical gen
eration and damage increase throughout pregnancy and protect the fetus, which, however, is subjected to a degree of oxidative stress. Oxidative stress peaks by the second trimester of pregnancy, ending what appears to be a vulnerable period for fetal health and gestational progress. Conditions restricted to pregnancy, such as gestational hypertension, insulin resistance and diabetes, exhibit ...
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