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Article: Oxidative stress response in Shigella & nonpathogenic gut bacteria
- Article from:
- Indian Journal of Medical Research
- Article date:
- July 1, 1998
- Author:
CopyrightCopyright Indian Council of Medical Research Jul 1998. Provided by ProQuest LLC. (Hide copyright information)
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The effect of oxidative stress in the form of exogenous H202 on the survival of four species of Shigella and two nonpathogenic Gram negative gut bacteria and the role of catalase as an antioxidant enzyme, neutralizing the effect of H.02 were examined. A significant decrease in the number of colony forming units (CFUs) after exposure to exogenous H202 (122 +/- 37), compared to control bacteria (218+/- 63, P < 0.001) was observed. There was an induction of catalase activity after exposure to exogenous H202 and the specific activity of catalase in H:02 exposed bacteria was significantly increased (2.88 +/- 1.25), compared to control bacteria (1.5+/- 0.44; P < 0.05). A direct correlation ...