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Early weaning induces jejunal ornithine decarboxylase and cell proliferation in neonatal rats
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The Journal of Nutrition
- Article date:
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October 1, 1998
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Copyright informationCopyright American Institute of Nutrition Oct 1998. Provided by ProQuest LLC. (Hide copyright information)
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Early Weaning Induces Jejunal Ornithine Decarboxylase and Cell Proliferation in Neonatal Rats1,2
Chuan-Hao Lin,3 Leena Correia, Ketan Tolia, Mark S. Gesell,* Vasundhara Tolia, Ping-Cheung Lee^ and Gordon D. Luk*
ABSTRACT Increased ornithine decarboxylase (ODC) activity is associated with rapid cell proliferation in many cell types. The cellular effects of early weaning on intestinal development are not well established. To investigate whether ODC is involved in intestinal growth after early weaning, we precociously weaned suckling rats on postnatal d 15 and followed through d 21 (6 d after early weaning). Age-matched suckling pups served as controls. Rat pups were killed 1, 2, 3 and 6 d ...
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