Article: Photothermal destruction of hair follicles explains photoepilation

NEw YORK - The mechanism of long-term photoepilation appears to involve selective photothermal destruction of the germinative areas of the hair follicle secondary to radiant energy absorption by melanin-containing cells, Neil S. Sadick, M.D., F.A.C.P., said.

"A number of lasers and flashlamp devices have come into clinical use or are undergoing investigation for hair removal, but the mechanism by which they induce hair loss has remained unknown. Our investigations indicate that the light treatment results in direct cell killing, while alterations of the cell cycle in terms of increased apoptosis or a prolongation of the telogen phase have little or no importance in mediating ...

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